September 17

29 comments

Epigenetics – An Introduction

By heheals

September 17, 2020




This sketch video about epigenetics was created by Armando Hasudungan, in collaboration with Professor Susan Clark and Dr Kate Patterson at the Garvan Institute of Medical Research. It has been created for a broad, non-expert audience to highlight key messages about the role epigenetics plays in biological processes like development and diseases such as cancer.

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  1. There's one thing I am confused about. So if the histones are wrapped around our genes, and say you become a smoker (but no one in your family tree extending hundreds of years smoked) and the chemical tag is added to the histones to make that gene become 'expressed', does that mean that the 'smoker gene' is predetermined? In other words, will I have a 'smoking gene' by default that is turned off, but will only be turned on if I smoke?

  2. Aren't electromagnetic fields a method of epigenetic modification? Also it seems that the mechanism of the placebo affect is also an epigenetic modifier. Great presentation, very well done.

  3. If some epigenetic information can be passed down from parent to child how does the sperm/egg know what and how well the heart cells and brain cells did when interacting with products of the environment?

  4. I hope someone would answer my question. I find the epigenetic and mendel's law are somewhat a paradox. As far as I understand, epigenetic regulate, so that only one gene is expressed. It decides the activation of the dna. Whereas in mendel, both genes are activated. I don't know how to formulate my question, but I hope someone understands my confusion

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