September 18


Epigenome: The symphony in your cells

By heheals

September 18, 2020

Almost every cell in your body has the same DNA sequence. So how come a heart cell is different from a brain cell? Cells use their DNA code in different ways, depending on their jobs. Just like orchestras can perform one piece of music in many different ways. A cell’s combined set of changes in gene expression is called its epigenome. This week Nature publishes a slew of new data on the epigenomic landscape in lots of different cells. Learn how epigenomics works in this video.

Read the latest research on epigenetics at



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  1. The first mapping of the epigenome.  What we eat affects the epigenome.  Most foods we eat are modified genetically by gene guns vs selection over dozens of generations

    I wonder how the GMO companies made sure any long term changes to the epigenome that occur when eating their products aren't harmful to the survival of humans if this was the first time it was mapped.

    No need to worry, I guess.  1000s of studies say they're safe, just like they did with smokes and leaded gasoline and paint.

  2. the video is fantastic but a Nature video should not mix up "genetic code" and "DNA sequence"! the genetic information (the music score) is encoded into the DNA sequence, while the genetic code is the table of correspondence between nucleotide triplets and amino acids. the two terms describe different objects and should not be confused!!! moreover, there is no human genetic code, since, for instance, the translation of mRNA into proteins follows different codes in the nucleus and in the mitochondrion.
    another point: at min 2.30, the voice says that: histons can affect "which genes are read and how many", the correct sentence in my opinion should be "which genes are read and with what intensity" or "which genes are read and how much"….
    who wrote this text?

  3. The fact that this video exists makes my entire life…my two deepest and seemingly unrelated passions, symphony orchestras and epigenetics, working together in one video? What I would give to be a flutist playing for a symphony explaining the epigenome…

  4. 1:20 – the violinist and flautist play on different octaves, which is different sheet music/notes/DNA. They should have just played the same notes in the same key but at different tempos or instruments. On the whole it was a great video though 🙂

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