September 21


The Epigenetic Clock: A Theory and Hope for Growing Old Gracefully | Keith Booher | TEDxTurtleRock

By heheals

September 21, 2020

“The world population is aging, especially in the West and the industrialized countries of Asia. In fact, the percentage of the population over the age of 65 is expected to more than double by the year 2050. An aging population presents many societal challenges as advanced age is the number one contributor to chronic ailments such as heart disease, cancer, neurological disorders, and more. It is imperative that meaningful and effective anti-aging interventions are identified and deployed in order to ease the transition from a younger to gradually older population.
Epigenetics involves the modification of gene expression without changing the underlying DNA sequence. Importantly, many recent scientific studies demonstrate the connection between epigenetics, especially DNA methylation, and aging. To date, analyzing changing DNA methylation patterns at key genes is the most accurate way to quantify the aging process. Understanding the connection between epigenetics and the aging process allows us to gain deeper insight into the mechanisms that cause aging, with the ultimate hope of devising interventions that will potentially lead to better health and longevity.
” Post-Doc scientist This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at



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  1. It’s not the alcohol, it’s the Resveratrol in the grapes, that slows aging. I really wish these people would make the distinction when they say that. There are less toxic ways of getting Resveratrol than ingesting alcohol. Cranberries have it, too. It’s misleading, even if popular, to say that. One may decide to ingest alcohol for other reasons (like the buzz), but don’t tout it as what slows the aging. Love that he references the Horvath clock. I’ll look up his company he mentions, to see if they have a clock available – but I’m definitely a bit of a chicken to find out my biological age. Next, I’m watching that Steve Horvath TED talk next – oh, more Friday night COVID-19 social isolation fun.

  2. The east and west should agree on the average age? Dude elderlies and growing old is the very core of eastern philosophy. You even mentioned that fountain which shows how obsessed the western culture is with death and getting old.

  3. The data on moderate alcohol consumption needs to separate out those of us who choose not to drink from those who have to abstain because of medical or sobriety reasons. This video continues the myth that drinking is beneficial.

  4. I am confused by your graph presented at 11:18 which depicts "% of Population" on Y axis compared to years 1940 through 2060 on the X axis. There is no obvious correlation between X and Y axes here. For example what age are you referring to in the Y axis? Age 50, 60, 70 , 80, 90? Depending on your variable used this graph changes the slope of your plot. This is a very generic presentation which can be summarized as we get older we also have to deal with an increase in infirmaries associated with aging.

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