Almost every one of our cells contains the same DNA, the same DNA code. So how can cells that contain the same DNA be so different?
Tagging DNA shows how tiny tags called methyl groups can be added to DNA to affect gene expression. In cancer, the pattern of methylation changes such that some genes that should be on are switched off and some genes that should be off are switched on.
Unlike the genetic code that can not be easily changed, the methylation or epigenetic pattern can be altered with drug therapy.
This video was funded by:
Inspiring Australia: http://www.innovation.gov.au/science/inspiringaustralia/Pages/default.aspx
Garvan Institute: http://www.garvan.org.au
Kate Patterson: http://garvan.org.au/research/capabilities/biodata-visualisation/team/katpat
VIZBIplus project: http://garvan.org.au/research/capabilities/biodata-visualisation/vizbiplus-project and http://www.vizbi.org/plus
Epigenetics Research at Garvan https://www.garvan.org.au/research/genomics-epigenetics/epigenetics-research