October 6

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Epigenetic Clocks: Which Has The Best Correlation For Aging and Age-Related Diseases?

By heheals

October 6, 2020




11 epigenetic clocks have been published since 2011, but which is best for predicting aging and age-related disease? In this video, I present findings from a recent publication, “Underlying features of epigenetic aging clocks in vitro and in vivo”, that compared data for 11 epigenetic clocks, and derived a new epigenetic clock, the meta-clock.

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heheals

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  1. This was a fantastic review mate, well done. The apparent potential of epigenetic clocks to be predictive of senescence and mitochondrial dysfunction could be quite important. We have no easily accessible
    ways to measure these, proxies are required

  2. It looks like the colon (yellow) cells most consistently move up and to the right in each graph for both DNAm age and chronological age, whereas buccal, or mouth, are all over the place, in the second figure.

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