October 12


Is Inheritance Really All In Our Genes?

By heheals

October 12, 2020

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Epigenetic inheritance is really weird, but is it real?
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↓ More info and sources below ↓

Crash Course Physics with Dr. Shini Somara: https://www.youtube.com/user/crashcourse

Want more on epigenetic inheritance? Start here:
Univ. of Utah’s Learn Genetics: http://learn.genetics.utah.edu/content/epigenetics/inheritance/
Virginia Hughes – “Epigenetics: The Sins of the Father” http://www.nature.com/news/epigenetics-the-sins-of-the-father-1.14816

Dig deeper:

Szyf, Moshe. “Nongenetic inheritance and transgenerational epigenetics.”Trends in molecular medicine 21.2 (2015): 134-144.
Sharma, Abhay. “Transgenerational epigenetic inheritance requires a much deeper analysis.” Trends in molecular medicine 21.5 (2015): 269-270.
Heard, Edith, and Robert A. Martienssen. “Transgenerational epigenetic inheritance: myths and mechanisms.” Cell 157.1 (2014): 95-109.
Rando, Oliver J. “Daddy issues: paternal effects on phenotype.” Cell 151.4 (2012): 702-708.
Jablonka, Eva, and Gal Raz. “Transgenerational epigenetic inheritance: prevalence, mechanisms, and implications for the study of heredity and evolution.” The Quarterly review of biology 84.2 (2009): 131-176.
Heijmans, Bastiaan T., et al. “Persistent epigenetic differences associated with prenatal exposure to famine in humans.” Proceedings of the National Academy of Sciences 105.44 (2008): 17046-17049.
Pembrey, Marcus, et al. “Human transgenerational responses to early-life experience: potential impact on development, health and biomedical research.” Journal of medical genetics (2014): jmedgenet-2014.

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  1. For 20 years I didn't know my birth father who left before I was born. Last year I finally found him and we were both surprised to find that we were similar in beliefs, personalities, even likes and dislikes even though my mother differed from us in many of these and hadn't told me much about him growing up

  2. I swear when I was in kindergarten I used to punish my left hand for doing tasks. I'd like to think it was because some poor ancestor of mine was getting a ruler across the knuckles by some crazy nun.

  3. Doesn't it mean that all the unhealthy people who didn't eat enough just died and did not have children? So only healthy people had children, giving them their genes

  4. Yes but it's also not all its cracked up to be either. Everybody is a mixed bag of good, bad and tradeoffs. Some people struggle because of inherited Genes and it's not healthy to view those as an inheritance. Equally important is that any gene that is advantageous shouldn't be embellished as that breeds in the person an aire of superiority. Simply put, nobody's perfect.

  5. "is inheritance really all in our genes; have some questions about epigenetics? We don't have any significant understanding of that, but here's a nothing video expressing that fact. Stay curious!"
    -It's okay to be smart

    "That taught me nothing. Did you mean 'it sucks to be smart'?"

  6. I think I found the reason of why I am so excruatingly thin, my parents, when they were little is also very thin, they've grown a lot fatter today, meanwhile I am still struggling to get fat enough, no matter how much I eat, I just won't get fat, and it's frustrating, so I guess my ability to burn fat is turned on all the time? is that's what's happening here?

  7. But we do receive more than just the DNA from our parents. We already know we get the mitochondria from our mothers. It shouldn’t be surprising we get other proteins during conception, and of course, other proteins through the placenta during pregnancy. We just probably don’t know what these effects these changes would have, or what exactly is being changed.

  8. Why did the mice being fed a high fat diet get fat? Because mice are herbivores and aren't evolved to eat a high fat diet, unlike hunans who just get full quickly and require less food when fed a high fat diet>(omnivores)

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