Webinar by Steve Horvath on the epigenetic clock method from July 26, 2018.
DNA methylation data have enabled accurate age estimates for any tissue across the entire life course. These ‘epigenetic clocks’ link developmental and maintenance processes to biological ageing, giving rise to a unified theory of life course.
a) Horvath (2013) DNA methylation age of human tissues and cell types. Genome Biology.PMID: 24138928 PMCID: PMC4015143 DOI: 10.1186/gb-2013-14-10-r115 https://www.ncbi.nlm.nih.gov/pubmed/24138928
b) Horvath and Raj (2018) DNA methylation-based biomarkers and the epigenetic clock theory of ageing. Nat Rev Genet. PMID: 29643443 DOI: 10.1038/s41576-018-0004-3